The group of Sophien Kamoun at The Sainsbury Laboratory (TSL), Norwich, UK, studies plant-pathogen coevolution and how it impacts mechanisms of virulence and immunity.

Visit periodically for updates on lab news and publications. You can also follow us on Twitter and keep up with the latest research and news on plant-microbe interactions via the scoop.it pages.

 

Farewell Yu @YuSugiharaY 🤗

Thank you for all your 21st century biologist skills: from the computer to the wet lab; from phylogenomics and evolution to genetics, biochemistry and structural biology. 💪🏻

Enjoy your new position in Japan 🇯🇵 You’ll do amazing! We’ll miss you!

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Belated welcome to Ioanna

@ioanna_mor portrayed here proudly holding her first BN-PAGE blot! Ioanna joins us from industry following a PhD at Imperial College on insects like mosquito and Drosophila. #MovingOutOfYourComfortZone#CelebratingDiversityhttps://tsl.ac.uk/about/people/ioanna-morianou

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New year lunch #2024 Yu, Madhu, Adeline, Pai, Andy, Jiorgos, Sophien, Selva, Mau and Ioanna @kamounlab

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Just published: Papers galore: A year-end update on immune receptor networks

These past few weeks have been bustling with activity in the field of NLR network biology, with no fewer than eight papers. Let’s dive into a roundup of these developments.

This article is available on a CC-BY license via Zenodo. Cite as: Contreras, M.P., and Kamoun, S. (2023) Papers galore: A year-end update on immune receptor networks. Zenodo. https://doi.org/10.5281/zenodo.10439409

Read it on Medium:

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#OpenMPMIPosters

Just like at the 2019 MPMI Congress, we published our 2023 MPMI Congress posters on Zenodo. Here is the list. Please read, use and cite.

Probing the oligomeric state of activated NLR immune receptors by blue native-polyacrylamide gel electrophoresis (BN-PAGE). Hsuan Pai; Mauricio P. Contreras; Clémence Marchal; Jiorgos Kourelis; Andrés Posbeyikian; Sophien Kamoun
https://zenodo.org/record/8146428

Biochemical basis of activation and inhibition of an NLR/PRR immune receptor network. Contreras, Mauricio P.; Pai, Hsuan; Selvaraj, Muniyandi; Toghani, AmirAli; Tumtas, Yasin; Yuen, Enoch L. H.; Duggan, Cian; Ahn, Hee-Kyung; Kourelis, Jiorgos; Harant, Adeline; Wu, Chih-Hang; Bozkurt, Tolga O.; Derevnina, Lida; Kamoun, Sophien
https://zenodo.org/record/8146518

An effector from the potato late blight pathogen hijacks the host ESCRT pathway to suppress an NLR/PRR immune receptor network. Jogi Madhuprakash; Adeline Harant; Samuel Shepherd; Hsuan Pai; David M. Lawson; Chih-Hang Wu; Tolga O. Bozkurt; Lida Derevnina; Sophien Kamoun; Mauricio P. Contreras
https://zenodo.org/record/8146559

The NLR immune receptor Pik-1 evolved to respond to fungal effectors of the AVR-Mgk family early in the evolution of Oryza and prior to rice domestication. Yu Sugihara; Aleksandra Białas; Thorsten Langner; A. Cristina Barragan; Jiorgos Kourelis; Yoshiko Abe; Koki Fujisaki; Mark J. Banfield; Ryohei Terauchi; Sophien Kamoun
https://zenodo.org/record/8147460

Pikobodies: What does it take to bioengineer NLR immune receptor-nanobody fusions. Jiorgos Kourelis; Clemence Marchal; Andres Posbeyikian; Adeline Harant; Sophien Kamoun
https://zenodo.org/record/8146575

NLR Bioengineering: Pikobodies confer systemic resistance to Potato virus X. Andres Posbeyikian; Clemence Marchal; Jiorgos Kourelis; Adeline Harant; Sophien Kamoun
https://zenodo.org/record/8146482

The Making of a Story — Communicate Your Research Effectively with Graphics
Hsuan Pai; Amelia H. Lovelace; Sophien Kamoun
https://zenodo.org/record/8146440

Another meeting at IBRC in Kitakami, Iwate, with the Teams of
@ryoheiterauchi @mjbanfield

This year with special guests Ayako @Ayako_Tsushima and Mina @mina_a_o

Thank you @royalsociety @jsps_sns for making it happen! 🇯🇵 🇬🇧 #BLASTOFF #plantsci #plantpath 

/via Rob Davies @ Eastern Daily Press and East Anglian Daily Times–there is a great article in which two researchers from Norwich Research Park Prof Sophien Kamoun of The Sainsbury Laboratory and Prof Diane Saunders of John Innes Centre share their...

/via Rob Davies @ Eastern Daily Press and East Anglian Daily Times–there is a great article in which two researchers from Norwich Research Park Prof Sophien Kamoun of The Sainsbury Laboratory and Prof Diane Saunders of John Innes Centre share their thoughts on how to mitigate the impending food crisis the world faces.
#makingsciencemainstream #changinglives

#SchoBozKa #SchoBozKaDeRella 2023 @downingcollege @Cambridge_Uni"Schobozka" is a portmanteau of the three researchers’ names (Schornack, Bozkurt, and Kamoun), more recently joined by Derevnina and Carella (DeRella). The group has been meeting annually since 2016.

DEFRA UK >> “Did you know it’s possible to delete 48 letters in the genetic code of a tomato? 🍅 🔬 This #BritishScienceWeek, we visit #STEM experts at @TheSainsburyLab. They’re using genome editing to make pathogen resistant plants 👇

DEFRA highlights Tomelo! The GE fungal resistant tomato. Feat. our very own Joe Win, Thorsten Langner and Clemence Marchal.

Check also the article by Mia Cerfonteyn “Why are we editing plant genes?”

Lab day out in Cambridge with a tour of the botanical Gardens courtesy of Dr. ⁦@dromius⁩